Sodium Hyaluronate



Sodium Hyaluronate at a glance

  • Salt form of hyaluronic acid
  • Excellent skin-replenishing ingredient
  • One gram can hold up to six liters of water
  • More readily absorbed into skin than hyaluronic acid
  • Available in different molecular weights for controlled penetration

Sodium Hyaluronate description

Sodium hyaluronate is the salt form of the skin-replenishing ingredient hyaluronic acid. It shares the same benefits as hyaluronic acid, including its remarkable ability to help skin retain a lot of moisture - one gram (or 0.03 oz.) of hyaluronic acid can hold up to six liters of water. Used on skin, it doesn’t hold that much water; instead, as a smart ingredient, sodium hyaluronate helps skin maintain water balance, which is critical to its healthy appearance. In addition to its moisture-binding (humectant) properties, sodium hyaluronate is also considered a postbiotic, meaning it can help nourish and maintain skin’s microbiome. The chief difference between hyaluronic acid and sodium hyaluronate is that sodium hyaluronate is more bioavailable - meaning skin more readily absorbs it than hyaluronic acid. This doesn’t necessarily mean it’s better than hyaluronic acid, merely that many skin care products contain both forms, so your skin sees maximum benefits. Both hyaluronic acid and sodium hyaluronate are available in different molecular weights for multi-level results (lower molecular weight can penetrate deeper into skin’s layers, where higher weights deliver immediate results on the surface).

Sodium Hyaluronate references

  • Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und Verwandte Gebiete, December 2017, pages 987-993
  • Journal of Cosmetic Dermatology, July 2014, pages 277-287
  • Journal of Clinical and Aesthetic Dermatology, October 2012, pages 20-23
  • DermatoEndocrinology, July-December 2012, pages 253-258
  • Journal of Drugs in Dermatology, September 2011, pages 990-1000

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.