Neopentyl Glycol Diethylhexanoate



Neopentyl Glycol Diethylhexanoate at a glance

  • Diester of neopentyl glycol and 2-ethylhexanoic acid
  • Emollient properties hydrate and soften skin
  • Helps thicken skin care formulas
  • CIR Expert Panel deemed safe for use in cosmetics

Neopentyl Glycol Diethylhexanoate description

Neopentyl glycol diethylhexanoate is the diester of neopentyl glycol, a solvent and texture enhancing agent, and 2-ethylhexanoic acid, a skin conditioning ingredient. This skin care ingredient assists skin in the retention of moisture due to its emollient properties. Emollient ingredients form a protective layer over skin, trapping much-needed moisture within while also providing a soft skin feel. It’s also utilized as a non-aqueous thickening agent in skin care products. As a raw material, neopentyl glycol diethylhexanoate appears as a light-yellow or clear colored liquid. The Cosmetic Ingredient Review Expert Panel ruled neopentyl glycol diethylhexanoate safe for use in cosmetics at current, wide-ranging levels (0.9-57%).

Neopentyl Glycol Diethylhexanoate references

  • ULProspector, Webpage, Accessed January 2023
  • Cosmetic Ingredient Review, November 2017, ePublication

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not Rated