Matrixyl 3000 Best Peptide Anti-Ageing Matrixyl 3000 at a glance Trademarked blend that includes two synthetic peptides with anti-aging benefits Proven to reduce wrinkle depth Calms signs of skin irritation Helps mitigate visible skin damage Matrixyl 3000 description Matrixyl™ 3000 is a trademarked blend that includes two synthetic peptides: palmitoyl tripeptide-1 (formerly known as palmitoyl oligopeptide) + palmitoyl tetrapeptide-7. These two “messenger” peptides (sometimes referred to as matrikines) work synergistically to send repair signals via skin’s surface that help mitigate visible skin damage and strengthen skin’s supportive elements. Studies have shown ongoing use can lead to a reduction in wrinkle depth. Glycerin, water, butylene glycol, carbomer and polysorbate 20 make up the rest of the Matrixyl™ 3000 blend. Along with smoothing the appearance of wrinkles, Matrixyl™ 3000 has been shown to calm visible signs of sensitisation. The suggested usage concentration of Matrixyl™ 3000 is 3%, although higher or lower amounts may be used depending on the formulary goals. The actual peptide concentration of this blend is much lower than 3% (peptides can work in surprisingly low amounts). Both peptides in Matrixyl™ 3000 have undergone independent safety/toxicology reviews and were deemed safe by the Cosmetic Ingredient Review Expert Panel. Related ingredients: Palmitoyl Tetrapeptide-7