Palmitoyl Tetrapeptide-7



Palmitoyl Tetrapeptide-7 at a glance

  • A synthetic peptide composed of four amino acids + palmitic acid
  • Proven to reduce factors in skin that trigger irritation and damage
  • Ongoing use helps restore a firmer feel and less lined appearance
  • Often used with other peptides for synergistic results

Palmitoyl Tetrapeptide-7 description

Synthetic peptide that’s part of Matrixyl 3000, which also contains palmitoyl oligopeptide, and is believed to work as a skin-restoring ingredient with anti-ageing benefits. This peptide is composed of four amino acids plus fatty acid palmitic acid to enhance stability and penetration into the skin. Peptides have different functions on skin, and this particular peptide, on its own or as part of Matrixyl 3000, helps to replenish skin’s surface and calm visible signs of sensitisation.

Palmitoyl Tetrapeptide-7 references

  • Cosmetics, November 2020, ePublication
  • International Journal of Toxicology, Volume 37, Supplement 3, November 2018, pages 90S–102S
  • Journal of Cosmetic Dermatology, June 2015, pages 152–160
  • Molecular Pharmaceutics, March 2013, pages 1,063-1,069
  • Plastic Surgical Nursing, April 2012, pages 71–72

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.