Isodecyl Neopentanoate



Isodecyl Neopentanoate at a glance

  • Synthetic emollient that also helps product flow
  • Delivers silicone-like esthetics with a light, dry finish
  • Helps oil-soluble ingredients penetrate skin more effectively
  • Made from fatty alcohols and a short-chain fatty acid

Isodecyl Neopentanoate description

Isodecyl neopentanoate is a synthetic emollient ester made from fatty alcohols and the short-chain fatty acid neopentanoic acid. It has silicone-like aesthetics and is used for a wide variety of purposes in cosmetics, including as an emollient. In addition, it leaves a dry, silky finish and can help deliver oil-soluble ingredients in to skin’s uppermost layers. Isodecyl neopentanoate also works to modify the rheology of cosmetic formulas, which is a fancy way to say it can positively impact a product’s flow, such as how quickly a sunscreen or shampoo is dispensed (does it flow freely or do you really have to work to get product out?). Usage levels of isodecyl neopentanoate in cosmetics ranges from 5–10%, although amounts lower than this may be present when this ingredient is part of a blend. It has been evaluated and deemed safe as used in cosmetics, assuming such products are formulated to be non-irritating.

Isodecyl Neopentanoate references

  • Annals of Dermatology and Venerology, June 2021, pages 77–93
  • International Journal of Toxicology, September 2015, pages 5S–69S
  • UL Prospector, accessed December 2022

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.