Hexapeptide-11

Best

Antioxidant

Hexapeptide-11 at a glance

  • Hexapeptide-11 is classified as a synthetic ingredient, although it can be initially derived from yeast (Saccharomyces cerevisiae) before undergoing synthesis for high purity. As a cosmetic ingredient, it is supplied as a powder or liquid solution. Suppliers recommend usage levels between 0.001% to 0.01%.

Hexapeptide-11 description

Hexapeptide-11 is what’s known in the world of skin care as a signaling peptide. It is made up of amino acids including alanine, phenylalanine, proline and valine. Research shows hexapeptide-11 has a positive impact on skin’s elasticity, as well as other factors related to skin’s firmness and hydration. Additionally, it offers antioxidant properties to help protect skin against environmental stressors. Preliminary research indicates that hexapeptide-11 shows promise for improving skin’s healthspan (a.k.a. longevity) due to the way it interacts with senescent (no longer performing their usual functions) cells. We’ll continue to watch this space and update as new research comes to light. Hexapeptide-11 is classified as a synthetic ingredient, although it can be initially derived from yeast (_Saccharomyces cerevisiae_) before undergoing synthesis for high purity. As a cosmetic ingredient, it is supplied as a powder or liquid solution. Suppliers recommend usage levels between 0.001% to 0.01%.

Hexapeptide-11 references

  • Active Peptide (supplier info), Accessed February 2023, ePublication
  • Personal Care Products Council, Accessed February 2023, ePublication
  • Journal of Cosmetic Dermatology, April 2022, pages 2,865–2,870
  • Skin Pharmacology and Physiology, June 2021, pages 194-201
  • Redox Biology, August 2015, pages 205-215

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings

Best

Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.

Good

Necessary to improve a formula's texture, stability, or penetration.

Average

Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.

Bad

There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.

Worst

May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.

unknown

We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.