Hesperidin Methyl Chalcone



Hesperidin Methyl Chalcone at a glance

  • Synthetic antioxidant
  • Derived from hesperidin, which is found in citrus fruit
  • Helps protect skin from UV damage
  • Possesses soothing and anti-redness properties

Hesperidin Methyl Chalcone description

Hesperidin methyl chalcone is a synthetic antioxidant and a derivative of the bioflavonoid hesperidin, which is found in citrus fruit. Research has shown that applied topically, hesperidin methyl chalcone helps protect skin from UV damage, though it is not an approved sunscreen ingredient. Studies also show it is a soothing ingredient that possesses calming and anti-redness properties. In its raw form, it is a yellow powder. Typical usage levels in skin care range from 0.1–3%. It is not known to be a safety or irritancy risk.

Hesperidin Methyl Chalcone references

  • Prospector Methyl Chalcone, Accessed March 2021, ePublication
  • Clinical, Cosmetic and Investigational, September 2018, pages 421-429
  • Photochemical & Photobiological Sciences, March 2016, pages 554-563

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.