Glycine at a glance

  • Amino acid that helps the body create proteins
  • Produced by the body
  • Is a skin replenishing ingredient
  • Chemically is considered the simplest amino acid

Glycine description

Glycine is an amino acid that helps the body create proteins. Chemically, it is considered the simplest amino acid and is found in many peptides. The body produces its own glycine, but it also can be consumed as part of a person’s diet. Applied topically, glycine (as with all amino acids) is a skin replenishing and hydrating ingredient, meaning it helps skin retain moisture for a more youthful look and feel.

Glycine references

  • Amino Acids in Nutrition and Health, August 2020, pages 187-199
  • Current Medicinal Chemistry, 2018, pages 5,512-5,527, ePublication
  • PLoS ONE, February 2018, ePublication
  • International Journal of Cosmetic Science, October 2009, pages 327-345

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not Rated