Glucosyl Hesperidin



Glucosyl Hesperidin at a glance

  • Synthetic water-soluble form of the flavonoid hesperidin
  • Has antioxidant properties + can improve barrier function
  • Has skin-soothing benefits
  • Some research shows it can improve the appearance of uneven skin tone

Glucosyl Hesperidin description

Glucosyl hesperidin is a water-soluble form of hesperidin, a flavonoid found in many citrus plants, as well as in evening primrose oil. Whereas hesperidin is natural, glycosyl hesperidin is synthetic. Its water solubility means it is more readily absorbed by the skin. Research shows hesperidin has antioxidant properties and when applied topically, can help improve skin’s barrier function. There are also studies showing it has skin-soothing benefits and that it can improve the appearance of uneven skin tone. Aside from its skin care use, glucosyl hesperidin is also used as a food additive and has been determined “generally ruled as safe” (GRAS) by the United States Food & Drug Administration.

Glucosyl Hesperidin references

  • Journal of Drug Delivery Science & Technology, February 2020, ePublication
  • Evidence Based Complementary and Alternative Medicine, April 2019, ePublication
  • Phytotherapy Research, September 2012, pages 1,272–1,277

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.