Zinc Gluconate



Zinc Gluconate description

The zinc salt of gluconic acid, a mild acid produced from the sugar glucose. Despite the in-part sugar origins, this is a synthetic ingredient that functions as a preservative. Interestingly, the human body produces gluconates on its own to assist in obtaining nutrients from minerals. There’s research showing oral consumption of zinc gluconate may be helpful for blemishes; however, it wasn’t compared with other oral options for blemishes, such as antibiotics and isotretinoin, an oral retinoid. Zinc gluconate is considered safe as used in cosmetics. t’s also used in over-the-counter oral lozenges designed to combat the common cold.

Zinc Gluconate references

  • Cosmetic Ingredient Review, September 2018, pages 1-62
  • Dermatology Research and Practice, July 2014, ePublication
  • European Journal of Dermatology, June 2000, pages 269-273

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.