Tetradecyl Aminobutyroylvalylaminobutyric Urea Acetate



Tetradecyl Aminobutyroylvalylaminobutyric Urea Acetate at a glance

  • Synthetic peptide helps improve skin’s hyaluronic acid content
  • Helps maintain surface hydration and smoothness
  • Contributes to a firmer look and feel
  • Not shown to improve wrinkle depth better than placebo

Tetradecyl Aminobutyroylvalylaminobutyric Urea Acetate description

Tetradecyl aminobutyroylvalylaminobutyric urea acetate (say that five times fast!) is a synthetic tripeptide said to help improve skin’s hyaluronic acid content. This improves its ability to maintain surface hydration and helps to visibly restore a firmer appearance. Clinical studies from this ingredient’s supplier show that it helps improve the “biomechanical properties” of skin. This means ongoing use helps to improve skin’s ability to bounce back when stretched, something which naturally declines with age and is compounded by cumulative environmental damage. It was also shown to smooth rough texture and decrease wrinkle volume, although the latter benefit was also achieved with a placebo product. These studies were done on human skin and objectively measured over a period of 8 weeks. In vitro data indicate that this peptide helps support skin’s underlying elements, further contributing to the look and feel of firmer, smoother skin. This peptide is supplied as a liquid, with the peptide combined with magnesium chloride and glycerin or similar substances to enhance skin compatibility and improve penetration. The recommended usage levels of tetradecyl aminobutyroylvalylaminobutyric urea acetate in such blends is 2–3%.

Tetradecyl Aminobutyroylvalylaminobutyric Urea Acetate references

  • International Journal of Peptide Research and Therapeutics, February 2019, pages 181–189
  • Clinical, Cosmetic, and Investigational Dermatology, May 2018, pages 253–253; and November 2017, pages 473–482

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.