Symphytum Officinale Callus Culture Extract

Good

Antioxidant

Symphytum Officinale Callus Culture Extract at a glance

  • Stem cell extract from the comfrey plant
  • Has antioxidant and soothing properties
  • Helps improve some visible signs of aging
  • Does not present the same problems for skin as pure comfrey

Symphytum Officinale Callus Culture Extract description

_Symphytum officinale_ callus culture extract is the cell extract from the roots of a plant commonly known as comfrey. Specifically, it’s the cell extract from a root callus, soft tissue that forms over a wounded plant surface and can produce growth itself; essentially, a stem cell extract. Much has been made in recent years of plant stem cells’ abilities to rejuvenate skin. Though a lot of it is overstated, research finds that _Symphytom officinale_ callus culture extract does exhibit antioxidant and calming abilities that help fight visible signs of aging. The phenolic compounds within this extract make it a worthwhile ingredient to consider in anti-aging formulas. One note: while comfrey extract itself has alkaloid content that can irritate skin, the same is not true of its callus culture extract. As of the time of this writing, the independent Cosmetic Ingredient Review panel has not reported on the safety of _Symphytum officinale_ callus culture extract as used in cosmetics. According to the supplier, use levels of _Symphytum officinale_ callus culture extract ranges from 0.4–1% in a water base that also contains isomalt, lecithin, and sodium benzoate.

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings

Best

Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.

Good

Necessary to improve a formula's texture, stability, or penetration.

Average

Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.

Bad

There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.

Worst

May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.

unknown

We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.