Superoxide Dismutase



Superoxide Dismutase at a glance

  • Enzyme found in the cells of living organisms
  • Breaks down potentially harmful oxygen molecules, making it a potent antioxidant
  • Has calming properties for skin
  • Some forms show promise in defending skin from UV damage

Superoxide Dismutase description

Superoxide dismutase (or SOD) is an enzyme found in the cells of living organisms. It breaks down potentially harmful oxygen molecules, defending the body from the effects of oxidative stress, which makes it a potent antioxidant. In the medical field, studies are underway to see if it can be used as a therapeutic treatment for numerous diseases. Topically, in addition to its antioxidant benefits, superoxide dismutase has shown promise for its calming properties for skin. Emerging science shows that superoxide dismutase extracted from certain plants might even have UV-protective abilities when applied to skin.

Superoxide Dismutase references

  • Molecules, March 2021, ePublication
  • Journal of Biotechnology, August 2019, pages 101-111
  • Journal of Cosmetic Dermatology, December 2018, pages 1,069-1,072
  • International Journal of Health Sciences, May-June 2018, pages 88–93

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.