Sh-Polypeptide-121 Best Peptide Anti-Ageing Soothing Sh-Polypeptide-121 at a glance Vegan, collagen-identical peptide made via fermentation Shown to reduce the look of wrinkles and boost skin’s resilience Soothing properties visibly reduce redness and puffiness Excellent synergy with vitamin C Sh-Polypeptide-121 description Sh-Polypeptide-121 is bio-identical vegan collagen signal peptide produced via bacterial fermentation. Research from the supplier has shown this single chain peptide can increase skin’s tensile strength by helping to bolster its supportive elements. This also helps smooth the appearance of wrinkles. Sh-polypeptide-121 has excellent synergy with vitamin C, with supplier studies showing the combination leads to a significant improvement in skin’s firm look and feel. It also has soothing properties that may play a role in reducing the appearance of puffy eyes and reddened skin. This peptide is supplied as a solution or a powder. Usage levels vary by format, with the recommended level for the solution being 2% and the more concentrated powder being at 0.1%.