Saccharide Isomerate



Saccharide Isomerate at a glance

  • Humectant derived from plant sugars
  • Attracts and hold moisture as it soothes
  • Has a natural affinity for skin

Saccharide Isomerate description

Saccharide isomerate is a complex mixture of hydrating corn-derived sugars which have moisture-binding (humectant) properties. The sugars are then isomerized, a process in which rearranges molecular structure to change the way a substance works and/or the results it has. In this case, the result closely matches the carbohydrates naturally present in skin’s natural moisturizing factor, NMF. This gives saccharide isomerate a natural affinity for skin, allowing it to provide prolonged hydration. Research indicates saccharide isomerate has an affinity for soothing and strengthening skin’s barrier by influencing key proteins skin’s uppermost layers need to ensure a smooth, intact surface that’s less vulnerable to environmental aggressors such as airborne pollutants. Usage levels based on clinical data on human skin range from 0.6–3%. It is considered safe as used in cosmetics and is most beneficial when used in leave-on formulas.

Saccharide Isomerate references

  • Microorganisms, October 2020, pages 1-16
  • International Journal of Cosmetics Science, October 2019, pages 411–424
  • Proceedings of the International Conference on Health Informatics and Medical Application Technology (ICHIMAT 2019), pages 411-417
  • Journal of the Medical Association of Thailand, 2014, pages 820-826
  • Cosmetics & Toiletries, September 2013, ePublication
  • Dry Skin and Moisturizers: Chemistry and Function, 2006, page 200

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not Rated