Polygonum Cuspidatum Root Extract



Polygonum Cuspidatum Root Extract at a glance

  • Excellent source of potent antioxidant resveratrol
  • Helps inhibit the formation of collagen-degrading substances in skin
  • Higher amounts shown to visibly improve hyperpigmentation
  • Capable of reducing signs of irritation

Polygonum Cuspidatum Root Extract description

_Polygonum cuspidatum_ root extract is a plant whose root is a good source of the potent polyphenolic antioxidant trans-resveratrol, which is considered the most bioavailable form of resveratrol. Also known as Japanese knotweed, Mexican bamboo, and, in Traditional Chinese Medicine as Hu Zhang, this plant not only helps thwart free radicals before they can damage skin, it also reduces signs of irritation. Research has also shown this plant extract can inhibit the formation of advanced glycation end-products, or AGEs. These are collagen-damaging proteins and fats that form in skin as a reaction from exposure to sugars. Left unchecked, AGEs can contribute to wrinkles and loss of firmness. Trans-resveratrol has been shown to fade hyperpigmentation when used in amounts of 1% or more; lower levels of _Polygonum cuspidatum_ root in skin care remain viable for antioxidant, soothing, and other benefits.

Polygonum Cuspidatum Root Extract references

  • Evidence-Based Complementary and Alternative Medicine, April 2020, ePublication
  • Food and Science Nutrition, June 2019, pages 2,006-2,016
  • Biomedicines, September 2018, ePublication
  • Evidence Based Complementary and Alternative Medicine, September 2013, ePublication
  • International Journal of Preventive Medicine, April 2013, Supplement 1, pages S1-S4
  • Journal of Inflammation, February 2008, ePublication

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.