Pentaerythrityl Tetraisostearate



No known benefits

Pentaerythrityl Tetraisostearate at a glance

  • Functions as a thickener, moisturizing ingredient, and binding agent
  • Derived from the fatty acid isostearic acid
  • Used in cosmetics in amounts from 0.1% to 55%
  • Deemed safe as used in skin care products

Pentaerythrityl Tetraisostearate description

Pentaerythrityl tetraisostearate is a non-aqueous ester that functions as a thickener, moisturising ingredient, and binding agent in skin care products. It is derived from isostearic acid, a type of fatty acid. Pentaerythrityl tetraisostearate is also known as PTIS. It is used in cosmetics in amounts from 0.1% to 55% (the highest concentration is in lipsticks, where it helps impart a glossy look as well as helps to disperse pigments). The independent Cosmetic Ingredient Review panel found that pentaerythrityl tetraisostearate is safe as used in cosmetics, with no irritation or sensitisation reported.

Pentaerythrityl Tetraisostearate references

  • International Journal of Toxicology, September 2015, pages 99S-112S

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.