Lactoperoxidase at a glance

  • Natural enzyme derived from milk
  • Also found in human saliva and mucosal systems
  • Antimicrobial + hydrating action helps restore skin’s microbiome
  • Considered safe as used in cosmetics

Lactoperoxidase description

Lactoperoxidase is an enzyme derived from milk. It is also found in the human body’s saliva and mucosal systems and serves as a defense against surface microbial infection. In the dairy industry, it is used to deter the proliferation of harmful bacteria in milk and milk products. In skin care, lactoperoxidase’s natural antimicrobial action helps restore skin’s surface flora (its microbiome), leading to a healthier, more hydrated look and feel, and an improvement in pore function. Lactoperoxidase is considered safe as used in cosmetics.

Lactoperoxidase references

  • Molecules, May 2021, pages 1–22
  • Antibiotics, April 2020, page 159
  • Enzyme Reseach, September 2014, ePublication
  • Journal of Applied Microbiology, May 2006, pages 1034–1042

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.