Lactobionic Acid



Lactobionic Acid at a glance

  • One of the polyhydroxy acids, chemically similar to AHAs
  • Slower penetration means a gentler experience
  • Exfoliates but is also a powerful humectant
  • Has antioxidant ability

Lactobionic Acid description

Lactobionic acid is a type of polyhydroxy acid (PHA) that functions as a skin exfoliant. It is chemically and functionally similar to AHAs (such as glycolic acid). The significant difference between lactobionic acid and AHAs is thatvlactobionic acid has a larger molecular structure, which limits its ability to penetrate the skin, resulting in less potential for sensitising side-effects. Polyhydroxy acids can also function as antioxidants and may promote some amount of improvement in skin’s surface strength.

Lactobionic Acid references

  • International Journal of Molecular Sciences, January 2021, pages 1–16 
  • Journal of Cosmetic Dermatology, December 2019, pages 1,705–1,710
  • International Journal of Dermatology, March 2019, pages 374–379
  • International Journal of Cosmetic Science, October 2012, pages 424–434
  • The Journal of Clinical and Aesthetic Dermatology, May 2012, pages 32–40
  • Dermatology Research and Practice, May 2021, pages 1–6
  • Cutis, February 2004, pages 3–13

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not Rated