Diisopropyl Sebacate



Diisopropyl Sebacate at a glance

  • Synthetic or plant-derived emollient and plasticizer
  • Helps soften skin + improve product aesthetics
  • Makes heavier emollients feel less greasy
  • Deemed safe as used in cosmetics

Diisopropyl Sebacate description

Diisopropyl sebacate is a diester made from reacting isopropyl alcohol and the pH adjusting-ingredient sebacic acid. It’s used in cosmetics for its emollient, plasticizing, and solvent properties. It may be plant-derived or synthetic. Note that despite isopropyl alcohol being part of what creates this ingredient, the result does not maintain the skin-irritating effects that type of alcohol has. Along with skin-softening benefits, it can also improve product spread, boost penetration of water-soluble ingredients, and help make heavier emollients such as petrolatum feel less greasy without losing their moisturizing abilities. This ingredient is supplied as a clear, colorless, odorless liquid with fluid properties. Fun fact: diisopropyl sebacate is used in underarm deodorants to prevent a whitening effect on skin (the kind that transfers to clothes). Usage levels of diisopropyl sebacate in skin care range from 1–10%. It is sometimes used as a replacement for silicones because it replicates some of the enviable sensory qualities this group has. Diisopropyl sebacate’s safety as used in cosmetics has been assessed. It’s considered non-irritating to skin and mildly irritating to eyes should direct contact occur.

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not Rated