Decarboxy Carnosine HCL



Decarboxy Carnosine HCL at a glance

  • Biomimetic peptide (meaning it is lab-engineered to emulate a natural peptide in the body)
  • Known for its antioxidant power and other anti-ageing effects
  • Also goes by the name carcinine
  • Derivative of another peptide (carnosine)

Decarboxy Carnosine HCL description

e Decarboxy carnosine HCL is a synthetic peptide that is biomimetic, meaning it is designed to emulate a natural peptide found in the body. It also goes by the name carcinine. In skin care, it’s most well-known for acting as an antioxidant, where it can help ward off the negative impacts environmental stressors have on skin. Suppliers of this ingredient tout its collagen-boosting benefits. At the time of this review, there isn’t enough peer-reviewed published research on decarboxy carnosine HCL to confirm that benefit, but it does look promising in terms of antiglycation effects. (Glycation is a process that impairs skin’s collagen and elastin, so inhibiting it is a good thing.) Because this ingredient is a derivative of carnosine, it is believed to offer many of the same anti-ageing benefits. Carnosine is a lab-engineered peptide that also occurs naturally in the body and plays a role in maintaining skin and bodily health.

Decarboxy Carnosine HCL references

  • Exsymol, Accessed January 2022, ePublication
  • BMJ Open, December 2020, pages 1-12
  • Oxidative Medicine and Cellular Longevity, September 2020, pages 1-15
  • Cosmetics, November 2018, pages 1-9

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not Rated