Ceramide NS



Ceramide NS at a glance

  • Natural component of skin that helps maintain barrier strength
  • As a skin care ingredient, aides in improving skin’s texture, hydration, and suppleness
  • Also helps boost skin’s defences against external stimuli
  • Can be derived from various sources, including yeast
  • Safety approved by the Cosmetic Ingredient Review Expert Panel

Ceramide NS description

Ceramide NS belongs to a larger group of ceramides that are naturally occurring, long chains of lipids (fats) that are major components of skin’s outer layers. In fact, skin’s composition is 50% ceramides. Ceramide NS in particular is a sphingosine-based ceramide, which when included in skin care formulas, helps skin produce more of its own ceramides. This helps skin better retain its moisture, while simultaneously strengthening its barrier against external stimuli. In general, ceramides work best when they’re combined with other replenishing ingredients like fatty acids and cholesterol. These lipid mixtures work in multiple ways to improve skin’s texture, suppleness, and help calm signs of sensitivity. Indeed, ceramides play a critical role in maintaining healthy skin. Ceramide NS can be derived from various sources both synthetic and natural, including yeast. The Cosmetic Ingredient Review Expert Panel’s 2020 assessment concluded that ceramide ingredients are safe in cosmetics in the present practises of use. Their survey data looked at personal care products containing concentrations between 0.001-0.006% of ceramide NS. This is a good example of how a seemingly low concentration of an ingredient can still have a noticeable effect on skin.

Ceramide NS references

  • International Journal of Toxicology, 2020, pages 5S-25S
  • PLoS ONE, October 2018, pages 1-18
  • Scientific Reports, November 2015, pages 1-11
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184
  • Journal of Lipid Research, September 2007, pages 1936-1943
  • American Journal of Clinical Dermatology, Volume 4, 2003, pages 107-129
  • Journal of Investigative Dermatology, November 2001, pages 1126-1136
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.