Ceramide NP



Ceramide NP at a glance

  • One of the most prevalent types of ceramides found naturally in skin
  • Can be created synthetically or sourced naturally from plants for use as a skin care ingredient
  • Helps improve the look and feel of dry or dehydrated skin thanks to its water retention properties
  • Reinforces skin’s barrier strength, so it better resists external stressors
  • Contributes to supple, resilient, hydrated skin overall

Ceramide NP description

Ceramide NP is one of several types of ceramides found naturally in skin. It plays a critical role as a major component of skin’s outer layers (healthy skin is generally composed of 50% ceramides, many of which are of the NP variety). “N” stands for the type of normal fatty acid correlated to this ingredient and “P” stands for its phytosphingosine base. Ceramides used in skin care can be created synthetically or sourced naturally from plants. Research shows skin care products containing ceramide NP can help improve the look and feel of dry or dehydrated skin thanks to its water retention properties. Ceramide NP has also been shown to reinforce skin’s barrier strength to better resist external stressors. Overall, it contributes to supple, resilient, hydrated skin. The Cosmetic Ingredient Review Expert Panel’s 2020 assessment concluded that ceramide ingredients are safe in cosmetics in the present practices of use. Their survey data looked at personal care products containing concentrations up to 0.00005-0.2% ceramide NP.

Ceramide NP references

  • International Journal of Toxicology, 2020, pages 5S-25S
  • International Journal of Molecular Sciences, August 2019, pages 1-15
  • Skin Pharmacology and Physiology, 2016, pages 135-147
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184
  • Journal of Lipid Research, July 2008, pages 1,466-1,476
  • Journal of Lipid Research, September 2007, pages 1936-1943
  • American Journal of Clinical Dermatology, 2003, pages 107-129
  • Contact Dermatitis, June 2002, pages 331-338
  • Journal of Investigative Dermatology, November 2001, pages 1,126-1,136
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not Rated