Ceramide NG



Ceramide NG at a glance

  • A specific ceramide found naturally in skin that can be replicated as a cosmetic ingredient 
  • Works to improve skin’s barrier strength, hydration, and suppleness  
  • Deemed a safe cosmetic ingredient by the Cosmetic Ingredient Review Expert Panel 
  • Formerly known as ceramide 2

Ceramide NG description

Ceramide NG (formerly known as ceramide 2) belongs to a larger group of ceramides that are found naturally in skin as long chains of lipids (fats). The “NG” refers to this ceramide’s sphinganine base. Healthy skin is made up of approximately 50% ceramides. Decreased levels of ceramides lead to weaker barrier strength, making skin more vulnerable to external stressors and dehydration. As a skin care ingredient, topical application of ceramide NG can step in to help fill this gap and replenish skin’s barrier, so it is better able to defend itself from external stimuli. Single ceramides work best when combined with other replenishing ingredients to improve skin’s hydration, resiliency, and suppleness.   The Cosmetic Ingredient Review Expert Panel’s 2020 assessment concluded that ceramide ingredients are safe in cosmetics in the present practices of use, typically no more than 0.01%. Ceramides used in skin care can be created synthetically (aka lab engineered) or sourced naturally from plants. 

Ceramide NG references

  • International Journal of Toxicology, 2020, pages 5S-25S      
  • International Journal of Molecular Sciences, August 2019, pages 1-15 
  •  Biochimica et Biophysica Acta, October 2014, pages 2473-2483  
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184  
  • Journal of Lipid Research, July 2008, pages 1,466-1,476  
  • Journal of Lipid Research, September 2007, pages 1936-1943  
  • American Journal of Clinical Dermatology, 2003, pages 107-129  
  • Journal of Investigative Dermatology, November 2001, pages 1,126-1,136  
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not Rated