Ceramide EOS



Ceramide EOS at a glance

  • Specific type of ceramide found naturally in skin that has a bio-identical skin care ingredient
  • Works optimally when combined with other ceramides + fatty acids and cholesterol
  • Helps improve skin’s barrier strength, hydration, and suppleness
  • Deemed a safe cosmetic ingredient by the Cosmetic Ingredient Review Expert Panel
  • Formerly known as ceramide 1

Ceramide EOS description

Ceramide EOS (formerly known as ceramide 1) belongs to a larger group of ceramides that are found naturally in skin as long chains of lipids (fats). The “EO” refers to the type of fatty acid correlated with the ingredient and “S” stands for this ceramide’s sphinogsine base. Healthy skin is made up of 50% ceramides, but when those ceramides decrease, skin’s barrier becomes weaker, making it more vulnerable to external stressors and dehydration. As a skin care ingredient, topical application of ceramide EOS can step in to help fill this gap and replenish skin’s barrier, so it is better able to defend itself from external stimuli. Ceramide EOS works best when combined with other ceramides + replenishing ingredients like fatty acids and cholesterol. Together, these lipid mixtures improve skin’s hydration, resiliency, and suppleness. They also play a signaling role in maintaining healthy skin. The Cosmetic Ingredient Review Expert Panel’s 2020 assessment concluded that ceramide ingredients are safe in cosmetics in the present practises of use. Their survey data looked at personal care products containing concentrations up to 0.01% of ceramide EOS. Ceramides used in skin care can be synthetic (aka lab engineered) or sourced naturally from plants.

Ceramide EOS references

  • International Journal of Toxicology, 2020, pages 5S-25S
  • International Journal of Molecular Sciences, August 2019, pages 1-15
  • Biochimica et Biophysica Acta, October 2014, pages 2473-2483
  • Journal of the American Academy of Dermatology, July 2014, pages 177-184
  • Journal of Lipid Research, July 2008, pages 1,466-1,476
  • Journal of Lipid Research, September 2007, pages 1936-1943
  • American Journal of Clinical Dermatology, 2003, pages 107-129
  • Journal of Investigative Dermatology, November 2001, pages 1,126-1,136
  • Skin Pharmacology and Applied Skin Physiology, September-October 2001, pages 261-271

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.