Acetyl Methionine



Acetyl Methionine at a glance

  • An amino acid, which are fundamental building blocks of all proteins in the body
  • Helps protect skin from environmental aggressors
  • Helps skin retain moisture
  • A derivative of methionine

Acetyl Methionine description

Acetyl methionine is an amino acid that is made in part from another amino acid, methionine. It’s created when one of the amine hydrogens within methionine’s structure is exchanged for an acetyl group. In an acetyl group, one part of a molecule is replaced with another, in this case a blend of three hydrogen, two carbon, and one oxygen molecule. This changes how the whole molecule works, in this case for the better! Amino acids are the building blocks of proteins and are critical to health. When used in skin care, amino acids serve as humectants, helping the skin to retain moisture. Some amino acids, including methionine and acetyl methionine, are also antioxidants, helping skin to mitigate damage brought on by environmental stressors, like the sun and pollution. Their ability to help the skin hold on to moisture and their knack for helping to protect skin from environmental stressors also makes them notable anti-aging agents. Amino acids work best when paired with other amino acids, natural moisturizing factors, and skin- restoring ingredients such as peptides. Acetyl methionine is considered safe for skin since it is also safe when used as a direct food additive.

Acetyl Methionine references

  • PubChem, Accessed June 2022, ePublication
  • Journal of Cosmetic Dermatology, Jan 2018, pages 138-144.
  • Molecular and Cellular Biochemistry, July 2019, pages 73-80.
  • International Journal of Toxicology, May 2017, pages 17S–56S

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not rated