Acetyl Dipeptide-1 Cetyl Ester Best Peptide Anti-Ageing Acetyl Dipeptide-1 Cetyl Ester at a glance Lab-made anti-ageing peptide that promotes firmer skin Bio-identical to a skin-natural peptide that aids elasticity Used as part of a blend with butylene glycol and hydroxyethylcellulose Soothing effect offsets stinging and burning sensations on skin Acetyl Dipeptide-1 Cetyl Ester description Acetyl dipeptide-1 cetyl ester is a lab-engineered synthetic peptide that combines acetic acid and cetyl alcohol with dipeptide-1, a peptide composed of amino acids arginine and tyrosine. Dipeptide-1 is found naturally in the body and plays a role in maintaining skin’s elasticity. Research has shown that topical application of this peptide protects collagen-making cells known as fibroblasts from the visible impact of glycation, a process in which destructive sugar molecules progressively weaken skin’s supportive elements. This ingredient has also been shown to thwart irritation on skin’s surface that would otherwise result in stinging or burning sensations. As such, it’s a very good option to pair with bio-active ingredients that can be more sensitising for some people. Recommended usage levels of this peptide range from 3–4%; however, since the peptide portion itself is part of a blend, the actual amount of peptide needed to gain benefit is much lower, in the parts per million level. It is considered safe as used in cosmetics.