Sodium Hydroxymethylglycinate



Sodium Hydroxymethylglycinate description

Sodium hydroxymethylglycinate is an amino acid derivative used as a skin-softening agent; can also function as a preservative in skin care products.

Sodium Hydroxymethylglycinate references

  •, Accessed March 2021, ePublication
  • Bioscience Reports, January 2020, ePublication
  • Investigative Ophthalmology and Visual Science, January 2018, pages 332-337
  • Dermatitis, March-April 2010, pages 109-110

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings


Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.


Necessary to improve a formula's texture, stability, or penetration.


Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.


There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.


May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.


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Not rated