Palmitoyl Tripeptide-5

Best

Peptide

Palmitoyl Tripeptide-5 at a glance

  • Synthetic tripeptide proven to help aging skin
  • Improves the look of fine lines and wrinkles
  • Encourages a firmer look and feel
  • Helps improve rough texture

Palmitoyl Tripeptide-5 description

Palmitoyl Tripeptide-5 is a synthetic, patented signal peptide made from the amino acids lysine and valine combined with the fatty acid palmitic acid, which aids penetration. It has a visible impact on skin’s firmness and also helps smooth the appearance of fine lines and wrinkles, including deep wrinkles. Peer-reviewed published research has shown that this peptide helps support several components of what’s known as skin’s extracellular matrix, including collagen and hyaluronic acid, so skin looks smoother and more youthful. It can also help inhibit environmentally-generated (as in sun exposure) damaging enzymes in skin that degrade its firmness and resilience. Use levels of palmitoyl tripeptide-5 in cosmetics range from 1–3% as a blend supplied in a water and glycerin base.

Palmitoyl Tripeptide-5 references

  • Molecules, March 2023, pages 1–12
  • Pharmaceuticals, July 2021, pages 1–22
  • Frontiers in Chemistry, October 2020, pages 1–8
  • Journal of Topical and Cosmetic Science, October 2020, pages 77–82
  • Indian Journal of Dermatology, Venereology and Leprology, January 2017, pages 9-18
  • Household and Personal Care Today, November/December 2015, pages 6–11
  • The Journal of Clinical and Aesthetic Dermatology, March 2009, pages 38–43

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings

Best

Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.

Good

Necessary to improve a formula's texture, stability, or penetration.

Average

Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.

Bad

There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.

Worst

May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.

unknown

We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.