Palmitoyl Tripeptide-38 Best Peptide Anti-Ageing Hydration Palmitoyl Tripeptide-38 at a glance Synthetic peptide that has signaling properties Plumps, hydrates & improves fullness Smooths to help the look of lines and wrinkles Helps support key proteins in skin’s extracellular matrix Effective at very low use levels as part of a blend Palmitoyl Tripeptide-38 description An ingredient manufactured by the brand Sederma under the trade name MATRIXYL synthe’6. The only research so far showing this ingredient’s benefit comes from the brand. That research followed 25 women between the ages of 42 to 70 years old who had forehead lines and crow’s feet. After two months, the women reported a decrease in signs of ageing of 31% in some cases, and up to 100% in others using a 2% concentration of MATRIXYL synthe’6 versus the placebo. Related ingredients: Peptides