Guaiazulene

Best

Antioxidant

Guaiazulene at a glance

  • Compound found in some essential oils
  • Has antioxidant properties
  • Also a soothing ingredient
  • Approved by the FDA as a colorant

Guaiazulene description

Guaiazulene is a naturally occurring compound found in the essential oils of many plants, including chamomile and guaiac wood. It is known for its vibrant blue color and is approved by the U.S. Food and Drug Administration as a human-safe colorant for cosmetics. In addition to its colorant properties, guaiazulene is known for its antioxidant benefits, fighting the free radical damage that can lead to premature signs of aging. Research also demonstrates it has impressive anti-inflammatory properties, helping alleviate redness and itching. All told, guaiazulene is a good addition to skin care products, especially if you suffer from skin sensitivity. Use levels of guiazulene in cosmetics range from 0.01–0.05% in leave-on products and up to 0.1% in rinse-off products. Although use levels are low, this speaks to the potent nature of this soothing powerhouse.

Guaiazulene references

  • UL Prospector, Website, Accessed August 2025
  • FDA.gov, Website, Accessed August 2025
  • Molecules, April 2024, pages 1-14
  • Life Sciences, March 2023, pages 1-17
  • Autophagy Reports, October 2022, pages 523-536

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings

Best

Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.

Good

Necessary to improve a formula's texture, stability, or penetration.

Average

Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.

Bad

There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.

Worst

May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.

unknown

We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.